新增讲座 《科学大讲堂 第256期》Sarah E. Reisman 教授：需求乃发明之母：天然产物及其催生的化学 - 2026-09-28 14:38 (#421)

* 地点：理学院一楼化学系C1038报告厅

## 主讲人简介

POSITION: 9/2020 to present Bren Professor Chemistry, California Institute of Technology, Pasadena, CA; 7/2015 to 7/2021 Executive Officer for Chemistry, California Institute of Technology, Pasadena, CA; 7/2015 to 7/2021 Investigator, Heritage Medical Research Institute California Institute of Technology, Pasadena, CA; 6/2014 to 8/2020 Professor of Chemistry, California Institute of Technology, Pasadena, CA; 6/2008 to 6/2014 Assistant Professor of Chemistry, California Institute of Technology, Pasadena, CA. EDUCATION & TRAINING: 2006 - 2008 Harvard University, Cambridge, MA National Institutes of Health Postdoctoral Fellow with Professor Eric N. Jacobsen; 2001 - 2006 Yale University, New Haven, CT Ph.D. in Organic Chemistry with Professor John L. Wood; 1997 - 2001 Connecticut College, New London, CT B.A. in Chemistry, Cum Laude Undergraduate research with Professor Timo V. Ovaska.

POSITION: 9/2020 to present Bren Professor Chemistry, California Institute of Technology, Pasadena, CA; 7/2015 to 7/2021 Executive Officer for Chemistry, California Institute of Technology, Pasadena, CA; 7/2015 to 7/2021 Investigator, Heritage Medical Research Institute, California Institute of Technology, Pasadena, CA; 6/2014 to 8/2020 Professor of Chemistry, California Institute of Technology, Pasadena, CA; 6/2008 to 6/2014 Assistant Professor of Chemistry, California Institute of Technology, Pasadena, CA. EDUCATION & TRAINING: 2006 - 2008 Harvard University, Cambridge, MA (National Institutes of Health Postdoctoral Fellow with Professor Eric N. Jacobsen); 2001 - 2006 Yale University, New Haven, CT (Ph.D. in Organic Chemistry with Professor John L. Wood); 1997 - 2001 Connecticut College, New London, CT (B.A. in Chemistry, Cum Laude, Undergraduate research with Professor Timo V. Ovaska).

## 讲座简介

The chemical synthesis of natural products provides an exciting platform from which to conduct fundamental research in chemistry and biology. Our group is currently pursuing the synthesis of several structurally complex natural products, with a particular focus on the development of new convergent fragment coupling and annulation strategies. The densely packed arrays of heteroatoms and stereogenic centers that constitute these polycyclic targets challenge the limits of current technology and inspire the development of new synthetic strategies and tactics. In parallel with our total synthesis efforts, we have an active program on the development of new reductive coupling reactions, including Ni-catalyzed asymmetric reactions of C(sp3) electrophiles and Sm-catalyzed reductive coupling reactions. This seminar will describe our work at the interface of total synthesis and Ni-catalysis.