Professor Tang Bo is an academician of the Chinese Academy of Sciences, a Leading Scientist at Laoshan Laboratory, a member of the Science and Technology Commission of the Ministry of Education, a member of the Chemistry Teaching Steering Committee, a Fellow of the Chinese Chemical Society, a Chief Scientist of the National Basic Research Program (973 Program), a recipient of the National Science Fund for Distinguished Young Scholars, and a member of the National Hundred, Thousand and Ten Thousand Talents Program. He leads the teaching and research team that was selected as one of the first“National University Huang Danian-style Teacher Teams.”Professor Tang’s research focuses on chemical imaging and sensing for life and health, development of analytical instruments, advanced photoresist and membrane separation materials, environmentally adaptive intelligent chemicals, and seawater hydrogen production. He has published over 500 significant papers as corresponding author (including co-corresponding) or first author in journals such as Nat. Synth., J. Am. Chem. Soc., Angew. Chem. Int. Ed. and Nat. Commun. His papers have been cited more than 59,000 times, with an H-index of 123. As the first inventor, he holds 113 authorized national invention patents, 11 of which have been transferred, and has received the National Invention and Entrepreneurship Award. He has been consecutively named an Elsevier Highly Cited Chinese Researcher for 11 years, and in 2024 received the ChemComm Outstanding Contribution Award from the Royal Society of Chemistry. As the principal investigator, he has won one second prize of the National Natural Science Award and two second prizes of the National Science and Technology Progress Award. He has led a number of national-level research projects, including the National Basic Research Program (973 Program), key projects of the National Natural Science Foundation of China, and the National Major Scientific Research Instrument Development Project of the National Natural Science Foundation of China.
Interfaces serve as organizational hubs in living systems—from material exchange barriers in organs and tissues, to nodes for intercellular recognition and signal integration, to energy-converting platforms on organelle membranes, and ultimately to receptor–ligand interactions at the molecular level. Across this multiscale hierarchy, interfaces collectively dictate homeostasis, signal transduction, and metabolic coupling. Consequently, chemical sensing and imaging that span this full spectrum of interfaces—from organs to molecules—are essential not only for unraveling the mechanisms underlying health and disease, but also for establishing rational design principles in synthetic biology and enabling the construction of artificial biological systems. Advancing such methodologies hinges on leveraging the quantum properties of electrons and photons as a foundational underpinning, and on integrating multimodal techniques including super-resolution fluorescence imaging, photoacoustic imaging, magnetic resonance imaging, electrochemical imaging, and NV-center-based quantum sensing. By addressing key challenges such as the trade-off between penetration depth and resolution, the complexity of in vivo detection, and signal interference, this approach aims to establish a multiscale, multi-interface methodological framework that bridges microscopic quantum measurements with digital twin modeling, ultimately enabling precise regulation of life processes and rational design in synthetic biology.
