课程大纲
COURSE SYLLABUS
1.
课程代码
/
名称
Course Code/Title
骨生物学基础研究进展 Advances in Bone Biology
2.
课程性质
Compulsory/Elective
专业选修课 Major Elective
3.
课程学分
/
学时
Course Credit/Hours
3 学分/48 学时 3 credits/48 hours
4.
授课语言
Teaching Language
中英双语 Chinese/English
5.
授课教师
Instructor(s)
曹惠玲， 副教授，南方科技大学医学院
caohl@sustech.edu.cn
0755-88018408
Cao Huiling, Associate Profeesor, School of Medicine, SUSTech
caohl@sustech.edu.cn
0755-88018408
6.
是否面向本科生开放
Open to undergraduates
or not
否
7.
先修要求
Pre-requisites
（如面向本科生开放，请注明区分内容。 If the course is open to
undergraduates, please indicate the difference.）
Biochemistry, Molecular biology
8.
教学目标
Course Objectives
（如面向本科生开放，请注明区分内容。 If the course is open to undergraduates, please indicate the
difference.）
本课程为医学或⽣物学专业研究⽣的专业选修课。本课程将从发育、⽣理及临床等各个⽅⾯介绍⾻⽣物学的研究进
展。通过本课程的学习，学⽣将了解⾻⽣物学的最新进展及研究热点，为学⽣将来的研究⼯作打下基础。
Advances in Bone Biology is a major elective course for graduate students majoring in medicine
or biology. It will introduce the recent advances in many developmental, physiological, and
clinical aspects of the bone biology. With completion of this course, students will understand the
latest advances and trends of bone biology, which may help lay a foundation for developing their
future research work.
9.
教学方法
Teaching Methods
（如面向本科生开放，请注明区分内容。 If the course is open to undergraduates, please indicate the
difference.）
专题讲授与专题讨论。
Lecture and discussion.
10.
教学内容
Course Contents
（如面向本科生开放，请注明区分内容。 If the course is open to undergraduates, please indicate the
difference.）
Section 1
骨生物学总论 Introduction of Bone biology
Section 2
骨骼中的细胞 Cells in bone
Section 3
骨骼发育 Skeleton development
Section 4
破骨细胞及骨吸收 Osteoclast and bone resorption
Section 5
成骨细胞及骨形成 Osteoblast and bone formation
Section 6
骨细胞与骨稳态 Osteocyte and bone homeostasis
Section 7
骨应力介导 Bone mechano-transduction
Section 8
骨质疏松症的治疗 Treatment of osteoporosis
Section 9
软骨发育与疾病 Cartilage Development and Disease
Section 10
骨性关节炎 Osteoarthritis
Section 11
类风湿性关节炎 Rheumatoid arthritis
Section 12
骨肿瘤及肿瘤骨转移 Bone tumour and tumour bone-metastasis
Section 13
骨血管 Bone vessels
Section 14
骨髓脂肪组织 Bone marrow adipose tissue
Section 15
骨免疫学 Osteoimmunology
Section 16
骨与骨外器官互作 Crosstalk Between Bone and Vital Organs
11.
课程考核
Course Assessment
（
○
1 考核形式 Form of examination；
○
2 .分数构成 grading policy；
○
3 如面向本科生开放，请注明区分内容。
If the course is open to undergraduates, please indicate the difference.）
○
1 考核形式
:
期末报告
Form of examination
：
Term report.
○
2
分数构成
:
出勤占
10%
、课堂表现占
30%,
期末报告占
60%
。
Grading policy
：
attendance 10%, in-class performance 30%, term report 60%.
12.
教材及其它参考资料
Textbook and Supplementary Readings
参考资料 Supplementary Readings:
1. 《Encyclopedia of Bone Biology》by Dr. Mone Zaidi et al, 2019. ISBN 978-0-12-814081-9.
2. 《骨发育与骨疾病的现代研究》,2018, ISBN 978-7-313-20582-7.
