(教学内容:中英双语)
本课程主要介绍病毒学的基本概念和知识,深入浅出地介绍病毒纷繁复杂的生活周期,病毒与宿主之间的作用关系,以及
病毒能够引发的相关疾病和抗病毒研究发展,并将结合代表性案例的方式向学生们展示病毒学基础研究在监测、预防、根
除病毒感染方面的重要作用和无穷潜力。
This course introduces the basic principles of Virology, including the life cycles of various viruses, the virus-host
interactions, the induced diseases, and the development of anti-viral therapeutic strategies, and presents the significant
values of virology studies on the monitoring, prevention, and treatment of many viral-associated human diseases.
(教学日历:中英双语)
我们为什么要研究病毒?Why do we study viruses?
• 病毒是自然界的有机组成部分; Viruses are indispensable.
• 病毒存在于一切生物体; Viruses survive in all of the species.
• 病毒具有广泛疾病性; Viruses are widely infectious.
• 病毒可以发展成为工具; Viruses can be a tool.
病毒的起源与分类 Viral origin and classification.
• 病毒的起源假说; The hypotheses of viral origin.
• 病毒的分类系统; Viral classification.
• 各类病毒的一般特征; The general characteristics of viruses.
代表性病毒专题 1:HIV 感染和人类的共生共存;
Typical case 1: The coexist of HIV infection and humans.
病毒的生活周期; Viral life cycle.
• 病毒的吸附与入侵; Viral attachment and entry.
• 病毒的复制; Viral replication.
• 病毒的装配和释放; Viral assembly and release.
病毒的结构差异; Viral structures.
• 病毒的基本结构; Viral basic structures.
• DNA 病毒的结构; The structures of DNA viruses.
• RNA 病毒的结构; The structures of RNA viruses.
• 朊病毒的特点; The structures of prion.
主题讨论 1:病毒结构和功能的一致性;
Discussion 1: The consistency of viral structures and functions.
病毒基因组和遗传学; Viral genetics.
• DNA 基因组; The genomes of DNA viruses.
• RNA 基因组; The genomes of RNA viruses.
• 病毒的遗传学分析; Viral genetic analysis.
病毒的感染和传播; Viral infection and transmission.
• 病毒感染的结局; The consequences of viral infection.
• 病毒的传播特性; Viral spreading features.
病毒的致病性; Viral pathogenicity.
• 病毒引发的急性疾病; Viral induced acute diseases.
• 病毒引发的慢性病; Viral included chronic diseases.
主题讨论 2:病毒与宿主的相互关系;
Discussion 2: The interactions between viruses and hosts.
代表性病毒专题 2:冠状病毒大流行;
Typical case 2: Coronaviruses-associated pandemics.
病毒与癌症; Viruses and cancers.
• 致瘤病毒的发现; The discovery of oncoviruses.
• 病毒转化的关键因素; The critical factors of virus-mediated transformation.
病毒与免疫系统的博弈; The survival game of viruses and immunity.
• 免疫系统的基本构成; The components of immunity.
• 病毒与免疫应答; Viral infection and immune response.
• 病毒与免疫治疗; Viral infection and immunotherapy.