1
课程详述
COURSE SPECIFICATION
以下课程信息可能根据实际授课需要或在课程检讨之后产生变动。如对课程有任何疑问，请
联系授课教师。
The course information as follows may be subject to change, either during the session because of unforeseen
circumstances, or following review of the course at the end of the session. Queries about the course should be
directed to the course instructor.
1. 课程名称 Course Title
生物材料与组织工程 Biomaterials and Tissue Engineering
2.
授课院系
Originating Department
生物医学工程系 Biomedical Engineering
3.
课程编号
Course Code
BMEB319
4. 课程学分 Credit Value
3
5.
课程类别
Course Type
专业核心课 Major Core Courses
6.
授课学期
Semester
春季 Spring
7.
授课语言
Teaching Language
英文 English
8.
授课教师、所属学系、联系方
式（如属团队授课，请列明其
他授课教师）
Instructor(s), Affiliation&
Contact
（For team teaching, please list
all instructors）
李凯，生物医学工程系，副教授
Kai Li, Biomedical Engineering, Associate Professor, lik@sustech.edu.cn
9.
实验员/助教、所属学系、联系
方式
Tutor/TA(s), Contact
待公布 To be announced
10.
选课人数限额(可不填)
Maximum Enrolment
（Optional）
2
11.
授课方式
Delivery Method
讲授
Lectures
习题/辅导/讨论
Tutorials
实验/实习
Lab/Practical
其它(请具体注明)
Other（Please specify）
总学时
Total
学时数
Credit Hours
48 48
12.
先修课程、其它学习要求
Pre-requisites or Other
Academic Requirements
无 None
13.
后续课程、其它学习规划
Courses for which this course
is a pre-requisite
无 None
14.
其它要求修读本课程的学系
Cross-listing Dept.
无 None
教学大纲及教学日历 SYLLABUS
15.
教学目标 Course Objectives
本课程将为学生介绍经典和现代生物材料在功能性组织工程领域中的应用研究，并为学生介绍该涵盖了多学科交叉的研究
领域，以培养其解决实践问题的能力。
To introduce students to classical and modern biomaterials as well as their applications in functional tissue engineering.
To attain a holistic appreciation of the various disciplines within biomaterials and tissue engineering and to develop the
ability to apply concepts to various problems.
16.
预达学习成果 Learning Outcomes
通过本课程的学习，学生可以了解多方面的知识，包括理解如何设计具有良好生物兼容性的材料体系，如植入支架等；
利用现代加工技术制备多功能的生物材料；设计用于疾病诊断与治疗的体系。
Through this course, the students should be able to understand the biological requirement for designed tissue
engineering systems (e.g., scaffold); fabricate multicomponent biomaterials using advanced manufacturing
technologies; design diagnostic and therapeutic materials systems.
17.
课程内容及教学日历 （如授课语言以英文为主，则课程内容介绍可以用英文；如团队教学或模块教学，教学日历须注明
主讲人）
Course Contents (in Parts/Chapters/Sections/Weeks. Please notify name of instructor for course section(s), if
this is a team teaching or module course.)
3
Lecture 1: 生物材料导论 Introduction to Modern Biomaterials （3 学时）
介绍生物材料的历史与发展进程，包括各种生物材料的特性及优缺点
To introduce the history and milestones in the development of biomaterials, including unique properties and strengths of
different biomaterials.
Lecture 2: 聚合物生物材料 Polymeric Biomaterials （3 学时）
聚合物生物材料的种类与性能
To introduce the types and properties of polymeric biomaterials, and their synthetic approaches
Lecture 3: 可 生 物 降 解 聚 合 物 ： 化 学 、 降 解 和 应 用 Biodegradable Polymers: Chemistry, Degradation and
Applications（3 学时）
聚合物生物材料的生物降解性、结构设计及在生物医学中的应用
To introduce the biodegradability of polymeric biomaterials and the mechanism of degradation, as well as their
applications in biomedical engineering
Lecture 4: 弹性体在心脏病学中的应用 Elastomers and Applications in Cardiology（3 学时）
弹性体在医用导管中的应用
To introduce the elastomers as catheters. connectors, etc.
Lecture 5: 中空纤维、水凝胶及其应用 Hollow Fibers, Hydrogels, and their Applications（3 学时）
中空纤维在肾脏病学以及水凝胶在眼科学中的应用
To introduce hollow fibers and hydrogels, as well as their applications in nephrology and ophthalmology
Lecture 6: 金属材料与骨移植 Metal Materials and Bone Grafting（3 学时）
医用金属材料及其在骨科医学（人工关节置换）中的应用
To introduce metal-based biomaterials and their applications in orthopaedics (e.g., artificial joint replacement)
Lecture 7: 玻璃、陶瓷、医用粘合剂和密封剂 Glasses, Ceramics, Medical Adhesives and Sealants（3 学时）
玻璃陶瓷以及医用粘合剂和密封剂的制备以及应用
To introduce the preparation and applications of glass metal、sealants in biomedical engineering
Lecture 8: 从生物材料到医疗器械 From Biomaterials to Medical Devices（3 学时）
医疗器械的种类与原理，以及生物材料在医疗器械中的作用
To introduce different types and design principles of biomedical devices, and the use of biomaterials in these devices
Lecture 9: 药物递送 Drug Delivery （3 学时）
药物递送体系的构建，包括纳米递送系统的制备和表征、多功能药物递送系统等
4
To introduce the design of drug delivery systems (DDS), including the synthesis and characterization of nanocarrriers
and multifunctional DDS.
Lecture 10: 组织工程导论 Introduction to Tissue Engineering（3 学时）
介绍组织工程的概念与发展进程，以及现代组织工程前沿
To introduce the history and milestones in the development of tissue engineering, and frontier of this research topic
Lecture 11: 细胞培养 Cell Culture（3 学时）
学习各种细胞培养（原代细胞，细胞株等）的基本操作与注意事项
To introduce operation and basic principles of cell culture (primary cells and cell lines)
Lecture 12: 细胞和组织冻存 Cryopreservation（3 学时）
细胞与组织冻存的基本操作，包括各种冻存方式的优缺点
To introduce the basic principles of cryopreservation of cells and tissues, including a review of various cryopreservation
approaches
Lecture 13: 骨组织工程 Tissue Engineering for Orthopaedics（3 学时）
组织工程在骨医学中的应用，包括选用的材料、支架构建与细胞源
Applications of tissue engineering in orthopaetics, and the choices of scaffold and cell resources
Lecture 14: 皮肤和血管组织工程 Tissue Engineering for Skin and Blood Vessels（3 学时）
介绍新型生物材料及其在不同疾病模型中皮肤及血管再生中的应用
To introduce new materials and their functions in reconstruction of skin and blood vessels in different disease models
Lecture 15: 功能化组织工程 Functional Tissue Engineering for Biomedical Applications（4 学时）
介绍组织工程前沿进展，文献综述
Literature review, to introduce the frontier in tissue engineering for therapeutic treatment
Lecture 16: 复习 Review（2 学时）
18.
教材及其它参考资料 Textbook and Supplementary Readings
Introduction to Biomedical Engineering (3rd Ed.), Enderle JD, Bronzino J (eds.), Academic Press, 2011.
Biomaterials for Tissue Engineering: Methods and Protocols (Methods in Molecular Biology), (1st Ed.), Humana Press
2018.
Introduction to Biomaterials: Basic Theory with Engineering Applications (1st Ed.), 2013, Cambridge University Press
2013.
课程评估 ASSESSMENT
5
19.
评估形式
Type of
Assessment
评估时间
Time
占考试总成绩百分比
% of final
score
违纪处罚
Penalty
备注
Notes
出勤 Attendance
20
课堂表现
Class
Performance
10
小测验
Quiz
课程项目 Projects
平时作业
Assignments
20
期中考试
Mid-Term Test
期末考试
Final Exam
50
期末报告
Final
Presentation
其它（可根据需要
改写以上评估方
式）
Others (The
above may be
modified as
necessary)
20.
记分方式 GRADING SYSTEM
A. 十三级等级制 Letter Grading
B. 二级记分制（通过/不通过） Pass/Fail Grading
课程审批 REVIEW AND APPROVAL
21.
本课程设置已经过以下责任人/委员会审议通过
This Course has been approved by the following person or committee of authority
生物医学工程系教学委员会
