1
课程详述
COURSE SPECIFICATION
联系授课教师。
The course information as follows may be subject to change, either during the session because of unforeseen
circumstances, or following review of the course at the end of the session. Queries about the course should be
directed to the course instructor.
1.
课程名称 Course Title
纳米生物医学概论 Introduction to Nano-Biomedicine
2.
授课院系
Originating Department
生物医学工程系 Department of Biomedical Engineering
3.
课程编号
Course Code
BMEB211
4.
课程学分 Credit Value
3
5.
课程类别
Course Type
专业选修课 Major Elective Courses
6.
授课学期
Semester
2 / 春季 Spring
7.
授课语言
Teaching Language
英文 English
8.
他授课教师)
Instructor(s), Affiliation&
Contact
For team teaching, please list
all instructors
蒋兴宇,生物医学工程系,讲席教授
jiang@sustc.edu.cn
Xingyu Jiang, Biomedical Engineering, Chair Professor
9.
/
方式
Tutor/TA(s), Contact
钟乐霓,生物医学工程系
11849027@mail.sustc.edu.cn
18682210049
Leni Zhong, Biomedical Engineering
10.
选课人数限额(不填)
Maximum Enrolment
Optional
2
授课方式
Delivery Method
习题/辅导/讨论
Tutorials
实验/实习
Lab/Practical
其它(请具体注明)
OtherPlease specify
总学时
Total
11.
学时数
Credit Hours
48
12.
先修课程、其它学习要求
Pre-requisites or Other
Academic Requirements
None
13.
后续课程、其它学习规划
Courses for which this course
is a pre-requisite
None
14.
其它要求修读本课程的学系
Cross-listing Dept.
生物医学工程系、生物系、化学系、材料科学与工程系、物理系、电子与电气
程系、计算机科学与工程系
教学大纲及教学日历 SYLLABUS
15.
教学目标 Course Objectives
通过课程内容的讲授和纳米生物技术研究方法及应用的介绍,使学生从纳米技术的研究方法到纳米技术在生物
领域的应用来透彻的了解纳米生物技术的重要作用。
By the introduction of nano-biotechnology research methods and applications, students can
thoroughly understand the important role of nano-biotechnology.
16.
预达学习成果 Learning Outcomes
通过本课程的学习,使学生了解和掌握纳米生物技术的研究内容、研究方法以及怎样利用纳米的技术手段来解
决生物领域的问题,熟悉和掌握纳米生物技术和传统的生物技术一些基本概念,为以后在研究生物医疗等领域
提供一个新的有力的武器。
Students will 1) understand and master the knowledge, research methods and how to use
nanotechnology to solve problems in the biomedicine; 2) understand some basic concepts in both
nano-biotechnology and traditional biotechnology. This course will provide a new set of tools
for biomedeicine.
17.
课程内容及教学日历 (如授课语言以英文为主,则课程内容介绍可以用英文;如团队教学或模块教学,教学日历须注明
主讲人)
Course Contents (in Parts/Chapters/Sections/Weeks. Please notify name of instructor for course section(s), if
this is a team teaching or module course.)
3
Section 1 纳米材料简介(3 学时
从纳米材料的起源、定义、类型以及工具进行综合性的介绍。
Section 1 Introduction
Introduction to nanomaterials, including origin, definition, types, and tools of nanotechnology.
Section 2 纳米生物表征(3 学时
常用的几种生物表征手段。
Section 2 Biological Characterization of nanomaterials
Methods for biological characterization of nanomaterials.
Section 3 纳米材料合成(3 学时
简单介绍不同纳米材料的合成方法。
Section 3 Fabrication methods
Introductions to different synthetic methods of nanomaterials.
Section 4 纳米生物分析(3 学时
主要介绍纳米技术在生物蛋白质检测与核酸检测方面的应用。
Section 4 Nanomaterials for biochemical assays
Introductions to applications of nanotechnology in protein and DNA detection.
Section 5 纳米材料表面修饰(3 学时)
介绍几种纳米材料表面修饰,通过不同表面修饰的纳米材料具有不同生物活性说明其应用价值。
Section 5 Modification of nanomaterials
Introductions to surface modification of nanomaterials and applications to adjusting the surface
modification of nanoparticles to regulate its biological properties.
Section 6 纳米生物 MEMS/NEMS3 学时)
从原理、制作工艺、应该简单介绍纳米生物 MEMS/NEMS
Section 6 BioMEMS/BioNEMS
Introduction to BioMEMS/BioNEMS, including design, fabrications, and applications.
Section 7 微流控芯片简介3 时)
从原理、制作工艺、应用简单介绍微流控芯片。
Section 7 Introductions to microfluidics.
Introduction to microfluidics chip, including design, fabrications, and applications.
Section 8 构建组织的体外模型/组织工程(3 时)
基于微流控芯片的体外模型构建,以及一些应用实例。
Section 8 Construction of in vitro models of tissues based on microfluidic.
In vitro models for tissues and tissue engineering based on microfluidics with some examples.
期中小组汇报(3 学时
以小组为单位,组内讨论并选择与课堂内容相关的课题,在课堂中进行展示。
4
Mid-term presentation
In groups, students discuss and select topics related to the content of the class and present it
in the classroom.
Section 9 于微流芯片的纳米材料合成3 学时
着重于利用微流控技术合成纳米材料。
Section 9 Synthesis of nanomaterials based on microfluidic chip.
Design of microfluidic channels for the synthesis of nanomaterials with unique features.
Section 10 米毒理学(3 学时)
简单介绍纳米材料的毒理学分析方法。
Section 10 Toxicology of nanomaterials
Introductions to toxicology of nanomaterials.
Section 11 米电子与生物医学(3 学时)
纳米电子技术应用与生物医学领域,如 MPC 在可拉伸穿戴设备上的应用。
Section 11 Nanoelectronics and biomedicine
Nanoelectronics in biomedicine, such as nanoscale/microscale materials for highly stretchable
bio-devices.
Section 12 个典型纳米生物医学问题(3 学时)
简单从几个纳米生物医学问题,联系到未来纳米生物医学的发展。
Section 12 Typical problems in biomedicine
Introduction of a few typical problems as examples for the future development of nanomedicine.
Section 13 米药物(3 学时)
从定义、作用机制、制备以及应用几个方面介绍纳米药物。
Section 13 Nano-drugs
Introduction to Nano-drug, including definition, mechanism, fabrications, and applications.
Section 14 米递送体系(3 学时)
纳米技术在药物递送中的应用,如靶向药物、CRISPR/Cas9 技术用于肿瘤治疗。
Section 14 Nanotechnology in drug delivery systems
Applications of nanotechnology in drug delivery, such as delivery of targeted therapy, and
CRISPR/Cas9 for tumor .
期末汇报(3 学时)
学生根据该学期学习到的纳米生物知识,选择相关课题,在课堂上进行交流。
Final presentation
According to the nano-biological knowledge learned in this semester, students choose related
topics and communicate in class.
18.
教材及其它参考资料 Textbook and Supplementary Readings
5
1. Introduction to NanoscienceGabor L. Hornyak ... [et al.].Boca Raton : CRC Press, c2008
2. 纳米生物检测, 庞代文,蒋兴宇,黄卫华主编, 北京 : 科学出版社,2014
3. 纳米技术在药物递送中的应用, 金义光主编, 北京 : 化学工业出版社,2015
课程评估 ASSESSMENT
19.
评估形式
Type of
Assessment
评估时间
Time
占考试总成绩百分比
% of final
score
违纪处罚
Penalty
备注
Notes
出勤 Attendance
课堂表现
Class
Performance
小测验
Quiz
10
实时反馈学生课堂学习情况;
Give feedbacks of the course
study in the classroom.
课程项目 Projects
30
以小组汇报的形式完成课程项目,
目的培养学生小组合作能力;
Finish a team project via
presentation and help students
to learn about teamwork.
平时作业
Assignments
20
通过期中、期末总结,让学生回顾
并总结近半学习的学习内容以及学
习收获;
Through mid-term and final
revision, help students to
summarize the whole course and
their results.
期中考试
Mid-Term Test
期末考试
Final Exam
期末报告
Final
Presentation
40
通过期末报告形式,培养学生独立
汇报能力;汇报内容与课堂学习内
容相关,考察学生对课程知识理解
程度;Help students to learn
how to give individual
presentations through a
presentation test in the final
exam, of which contents will
be highly related to the
course.
其它(可根据需
改写以上评估方
式)
Others (The
above may be
modified as
necessary)
6
20.
记分方式 GRADING SYSTEM
A. 十三级等级制 Letter Grading
B. 二级记分制(通/不通过) Pass/Fail Grading
课程审批 REVIEW AND APPROVAL
21.
本课程设置已经过以下责任人/员会审议通过
This Course has been approved by the following person or committee of authority