课程大纲

COURSE SYLLABUS

课程代码/名称

Course Code/Title

骨骼组织工程/Bone Tissue Engineering

课程性质

Compulsory/Elective

Elective

课程学分/学时

Course Credit/Hours

3 学分/48 学时 3 credits/48 hours

授课语言

Teaching Language

英语/English

授课教师

Instructor(s)

刘超/Chao Liu

先修要求

Pre-requisites

无/Not applicable

教学目标

Course Objectives

This course discusses bone tissue engineering from the current clinical standards to the most recent

developments. Bone tissue engineering strategies will be introduced from biochemical and biomechanical

roles of the major cell types found the bone: osteoblasts, osteoclasts, vascular endothelial cells and their

respective progenitors. In addition, tissues that are associated with the bone will be introduced.

The students will learn about the latest advances in the field of bone tissue engineering. The students will

also become proficient at interpreting data common in bone tissue engineering such as MicroCT, histology,

immunohistochemistry, and immunofluorescent microscopy.

教学方法

Teaching Methods

Teaching material will be gathered from text books and scientific journal articles.

Group discussions will be used to critically analyze scientific results and engineering designs.

Each student will complete a written report of a related topic, and give a presentation to the class.

教学内容

Course Contents

Section 1

Bone developmental biology

Section 2

Bone cell biology: MSC, osteoblasts, osteocytes, osteoclasts

Section 3

The organic and inorganic matrices

Section 4

Signaling molecules

Section 5

Polymers in bone tissue engineering

Section 6

Bone scaffold design

Section 7

Animal models

Section 8

Biomechanics

Section 9

Clinical applications – cranial facial and dental

Section 10

Clinical applications – spine and orthopedics

…………