课程大纲
COURSE SYLLABUS
1.
课程代码/名称
Course Code/Title
细胞与分子免疫学
(Cellular and Molecular Immunology)
2.
课程性质
Compulsory/Elective
选修 Elective
3.
课程学分/学时
Course Credit/Hours
3/48
4.
授课语言
Teaching Language
中英双语 (English and Chinese)
5.
授课教师
Instructor(s)
欧西军 (OU Xijun)
6.
是否面向本科生开放
Open to undergraduates
or not
否（no）
7.
先修要求
Pre-requisites
（如面向本科生开放，请注明区分内容。
If the course is open to
undergraduates, please indicate the difference.）
生物化学; 细胞生物学; 分子生物学
Biochemistry; Cell Biology;
Molecular Biology
8.
教学目标
Course Objectives
（如面向本科生开放，请注明区分内容。
If the course is open to undergraduates, please indicate the
difference.）
本课程面向研究生，着重帮助学生在细胞和分子水平上了解免疫系统的结构、功能及其与疾病的关
系。
This course will provide postgraduate students with a comprehensive understanding of immune system
structure and function, as well as the clinical correlates in infectious diseases, cancer and autoimmunity.
9.
教学方法
Teaching Methods
（如面向本科生开放，请注明区分内容。
If the course is open to undergraduates, please indicate the
difference.）
课堂讲授基本理论概念和前沿进展，学生讨论前沿问题和研究思路。
The teaching consists of lectures, group and discussion exercises.
10.
教学内容
Course Contents
（如面向本科生开放，请注明区分内容。 If the course is open to undergraduates, please indicate the
difference.）
Section 1
免疫系统简介
2
学时
Overview of Immune System 2 hours
Section 2
白细胞归巢与炎症
2
学时
Leukocyte Homing and Inflammation 2 hours
Section 3
天然免疫
6
学时
Innate Immunity 6 hours
Section 4
抗体
3
学时
Antibody 3 hours
Section 5
MHC
与抗原递呈
1
学时
MHC and Antigen Presentation 1 hours
Section 6
T
细胞受体结构和信号传导
3
学时
TCR Structure and Signal Transduction
3 hours
Section 7
T
细胞活化
2
学时
T Cell Activation 2 hours
Section 8
T
细胞发育
2
学时
T Cell Development 2 hours
Section 9
辅助性
T
细胞和细胞毒性
T
细胞
3
学时
Th Subsets and Cytotoxic T
Lymphocyte 3 hours
Section 10
T
细胞耐受
2
学时
T Cell Tolerance 2 hours
Section 11
B
细胞发育和耐受
2
学时
B Cell Development and Tolerance 2 hours
Section 12
B
细胞活化
2
学时
B Cell Activation 2 hours
Section 13
肿瘤免疫
2
学时
Tumor Immunology 2 hour
Section 14
病毒免疫
2
学时
Viral Immunity 2 hours
Section 15
自身免疫
2
学时
Autoimmunity 2 hours
Section 16
课堂报告与讨论
12
学时
Oral Presentation and Discussion 12 hours
11.
课程考核
Course Assessment
（
○
1 考核形式 Form of examination；
○
2 .分数构成 grading policy；
○
3 如面向本科生开放，请注明区分内容。
If the course is open to undergraduates, please indicate the difference.）
出勤 attendance (10 points)
课堂表现 performance (10 points)
课堂报告 presentation (40 points)
期末考试
final exam (40 points)
12.
教材及其它参考资料
Textbook and Supplementary Readings
Kuby Immunology, 7th edition, Judith A. Owen et al.
Cellular and Molecular Immunology, 8th edition, Abul K. Abbas et al.
