1
课程详述
COURSE SPECIFICATION
以下课程信息可能根据实际授课需要或在课程检讨之后产生变动。如对课程有任何疑问，请
联系授课教师。
The course information as follows may be subject to change, either during the session because of unforeseen
circumstances, or following review of the course at the end of the session. Queries about the course should be
directed to the course instructor.
1.
课程名称 Course Title
微生物学 Microbiology
2.
授课院系
Originating Department
生物系 Department of Biology
3.
课程编号
Course Code
BIO203
4.
课程学分 Credit Value
3
5.
课程类别
Course Type
专业基础课（生物科学、生物技术专业） Major Foundational Courses(Biological
Sciences, Biotechnology Majors)
专业选修课（生物信息学专业） Major Elective Courses(Bioinformatics)
6.
授课学期
Semester
春季 Spring / 秋季 Fall
7.
授课语言
Teaching Language
英文 English
8.
授课教师、所属学系、联系方
式（如属团队授课，请列明其
他授课教师）
Instructor(s), Affiliation&
Contact
（For team teaching, please list
all instructors）
孙 颖 、 生 物 系 、 联 系 方 式 ： sun.y@sustech.edu.cn ( Dr. Ying Sun, Department of
Biology, sun.y@sustech.edu.cn)
欧西军、生物系、联系方式 ouxj@sustech.edu.cn ( Dr. Xijun Ou, Department of Biology,
ouxj@sustech.edu.cn)
9.
实验员/助教、所属学系、联系
方式
Tutor/TA(s), Contact
待公布 To be announced
10.
选课人数限额(可不填)
Maximum Enrolment
（Optional）
60
授课方式
Delivery Method
讲授
Lectures
习题/辅导/讨论
Tutorials
实验/实习
Lab/Practical
其它(请具体注明)
Other（Please specify）
总学时
Total
11.
学时数
Credit Hours
32
8
8(Oral Presentation by
Students)
48
2
12.
先修课程、其它学习要求
Pre-requisites or Other
Academic Requirements
无 None
13.
后续课程、其它学习规划
Courses for which this course
is a pre-requisite
无 None
14.
其它要求修读本课程的学系
Cross-listing Dept.
无 None
教学大纲及教学日历 SYLLABUS
15.
教学目标 Course Objectives
通过对本课程的学习，使学生能够了解和掌握如下几个方面：
1.对微生物的历史与现状有初步了解
2.了解微生物的基本结构和特性
3.了解微生物的生长和代谢途径
4.了解微生物的分子生物学和遗传学特性
5.了解微生物与生态环境和人类的关系
This course aims to introduce students to the fundamentals of identification, structure, physiology, and genetics of
microorganisms; and the importance of microorganisms in human health, the environment, and in biotechnology.
16.
预达学习成果 Learning Outcomes
通过对本课程的学习，使学生能够了解和掌握如下几个方面：
6.对微生物的历史与现状有初步了解
7.了解微生物的基本结构和特性
8.了解微生物的生长和代谢途径
9.了解微生物的分子生物学和遗传学特性
10.了解微生物与生态环境和人类的关系
（ This course aims to introduce students to the fundamentals of identification, structure, physiology, and genetics of
microorganisms; and the importance of microorganisms in human health, the environment, and in biotechnology. ）
17.
课程内容及教学日历 （如授课语言以英文为主，则课程内容介绍可以用英文；如团队教学或模块教学，教学日历须注明
主讲人）
Course Contents (in Parts/Chapters/Sections/Weeks. Please notify name of instructor for course section(s), if
this is a team teaching or module course.)
3
Week
Periods
Topic
1
2
The history and scope of
microbiology
1,2
4
Prokaryotic and eukaryotic cell
structure and function
3
2
Quiz
3,4
4
Microbial nutrition and growth
5
2
Control of microorganisms
5
2
Quiz
6
2
Microbial metabolism and bacterial
genome expression
7
4
The diversity of the microbial world
(Bacteria and Archaea)
8
2
Quiz
9
2
The diversity of the microbial world
(Protists and Fungi)
10
2
Infection and pathogenicity
11
2
Quiz
11
2
Oral presentation (by students)
12, 13
4
Non-specific and specific immunity
13
2
Oral presentation (by students)
14
2
Microbial diseases detection and
control
15
2
Oral presentation (by students)
15
2
Applied microbiology
16
2
Oral presentation (by students)
4
Chapter 1: The history and scope of microbiology
1.1 Members of the Microbial World
1.2 The Discovery of Microorganisms
1.3 The Conflict over Spontaneous Generation
1.4 The Golden Age of Microbiology
1.5 The Development of Industrial Microbiology and Microbial Ecology
1.6 The Scope and Relevance of Microbiology
1.7 The Future of Microbiology
Key and difficulty: the history, current situation and future of microbiology
Chapter 2: Prokaryotic and eukaryotic cell structure and function
3.1 An Overview of Procaryotic Cell Structure
3.2 Procaryotic Cell Membranes
3.3 The Cytoplasmic Matrix
3.4 The Nucleoid
3.5 Plasmids
3.6 The Bacterial Cell Wall
3.7 Archaeal Cell Walls
3.8 Protein Secretion in Procaryotes
3.9 Components External to the Cell Wall
3.10 Chemotaxis
3.11 The Bacterial Endospore
4.1 An Overview of Eucaryotic Cell Structure
4.2 The Plasma Membrane and Membrane Structure
4.3 The Cytoplasmic Matrix, Microfilaments, Intermediate Filaments, and Microtubules
4.4 Organelles of the Biosynthetic-Secretory and Endocytic Pathways
4.5 Eucaryotic Ribosomes
4.6 Mitochondria
4.7 Chloroplasts
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4.8 The Nucleus and Cell Division
4.9 External Cell Coverings
4.10 Cilia and Flagella
4.11 Comparison of Procaryotic and Eucaryotic Cells
Key and difficulty: the differences between prokaryotic and eukaryotic cell.
Chapter 3: Microbial nutrition and growth
5.1 The Common Nutrient Requirements
5.2 Requirements for Carbon, Hydrogen, Oxygen, and Electrons
5.3 Nutritional Types of Microorganisms
5.4 Requirements for Nitrogen, Phosphorus, and Sulfur
5.5 Growth Factors
5.6 Uptake of Nutrients by the Cell
5.7 Culture Media
5.8 Isolation of Pure Cultures
6.1 The Procaryotic Cell Cycle
6.2 The Growth Curve
6.3 Measurement of Microbial Growth
6.4 The Continuous Culture of Microorganisms
6.5 The Influence of Environmental Factors on Growth
6.6 Microbial Growth in Natural Environments
Key and difficulty: the basic requirements for microbial growth
Chapter 4: Control of microorganisms
7.1 Definitions of Frequently Used Terms
7.2 The Pattern of Microbial Death
7.3 Conditions Influencing the Effectiveness of Antimicrobial Agents
7.4 The Use of Physical Methods in Control
7.5 The Use of Chemical Agents in Control
7.6 Evaluation of Antimicrobial Agent Effectiveness
6
Key and difficulty: understand the mechanisms how antibiotics kill microorganisms
Chapter 5: The diversity of the microbial world (Bacteria and Archaea)
Microbial Evolution,Taxonomy, and Diversity
The Archaea
Bacteria: The Deinococci and Nonproteobacteria Gram Negatives
Bacteria: The Proteobacteria
Bacteria: The Low G C Gram Positives
Bacteria: The High G C Gram Positives
Key and difficulty: the characteristics of bacteria and archaea
Chapter 6: The diversity of the microbial world (Protists and Fungi)
The Protists
The Fungi (Eumycota)
Key and difficulty: the characteristics of protists and fungi
Chapter 7: Viruses
16.1 Early Development of Virology
16.2 General Properties of Viruses
16.3 The Structure of Viruses
16.4 Virus Reproduction
16.5 The Cultivation of Viruses
16.6 Virus Purification and Assays
16.7 Principles of Virus Taxonomy
17.1 Classification of Bacterial and Archaeal Viruses
17.2 Virulent Double-Stranded DNA Phages
17.3 Single-Stranded DNA Phages
17.4 RNA Phages
17.5 Temperate Bacteriophages and Lysogeny
17.6 Bacteriophage Genomes
18.1 Taxonomy of Eucaryotic Viruses
7
18.2 Reproduction of Vertebrate Viruses
18.3 Cytocidal Infections and Cell Damage
18.4 Persistent, Latent, and Slow Virus Infections
18.5 Viruses and Cancer
18.6 Plant Viruses
18.7 Viruses of Fungi and Protists
18.8 Insect Viruses
18.9 Viroids and Virusoids
18.10 Prions
Key and difficulty: the viral cycle
Chapter 8: Infection and pathogenicity
33.1 Host-Parasite Relationships
33.2 Pathogenesis of Viral Diseases
33.3 Overview of Bacterial Pathogenesis
33.4 Toxigenicity
33.5 Host Defense Against Microbial Invasion
33.6 Microbial Mechanisms for Escaping Host Defenses
Key and difficulty: how pathogens cause infection
Chapter 9: Non-specific and specific immunity
31.1 Overview of Host Resistance
31.2 Cells, Tissues, and Organs of the Immune System
31.3 Phagocytosis
31.4 Inflammation
31.5 Physical Barriers in Nonspecific (Innate) Resistance
31.6 Chemical Mediators in Nonspecific (Innate) Resistance
32.1 Overview of Specific (Adaptive) Immunity
32.2 Antigens
32.3 Types of Specific (Adaptive) Immunity
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32.4 Recognition of Foreignness
32.5 T Cell Biology
32.6 B Cell Biology
32.7 Antibodies
32.8 Action of Antibodies
32.9 Summary: The Role of Antibodies
and Lymphocytes in Immune Defense
32.10 Acquired Immune Tolerance
32.11 Immune Disorders
Key and difficulty: the differences between innate and adaptive immunity
Chapter 10: Microbial diseases detection and control
35.1 Specimens
35.2 Identification of Microorganisms from Specimens
35.3 Clinical Immunology
35.4 Susceptibility Testing
35.5 Computers in Clinical Microbiology
34.1 The Development of Chemotherapy
34.2 General Characteristics of Antimicrobial Drugs
34.3 Determining the Level of Antimicrobial Activity
34.4 Antibacterial Drugs
34.5 Factors Influencing Antimicrobial Drug Effectiveness
34.6 Drug Resistance
34.7 Antifungal Drugs
34.8 Antiviral Drugs
34.9 Antiprotozoan Drugs
Key and difficulty: how to define pathogens
Chapter 11: Applied microbiology
41.1 Water Purification and Sanitary Analysis
9
41.2 Wastewater Treatment
41.3 Microorganisms Used in Industrial Microbiology
41.4 Microorganism Growth in Controlled Environments
41.5 Major Products of Industrial Microbiology
41.6 Biodegradation and Bioremediation by Natural Communities
41.7 Bioaugmentation
41.8 Microbes As Products
41.9 Impacts of Microbial Biotechnology
Key and difficulty: microorganisms used in industry
18.
教材及其它参考资料 Textbook and Supplementary Readings
Recommended Textbook:
1. Prescott’s microbiology, 9th edition
By Joanne, Linda and Christopher (McGraw-Hill International Edition)
课程评估 ASSESSMENT
19.
评估形式
Type of
Assessment
评估时间
Time
占考试总成绩百分比
% of final
score
违纪处罚
Penalty
备注
Notes
出勤 Attendance
5
课堂表现
Class
Performance
5
小测验
Quiz
20
课程项目 Projects
20
平时作业
Assignments
期中考试
Mid-Term Test
期末考试
Final Exam
50
期末报告
Final
Presentation
其它（可根据需要
改写以上评估方
式）
Others (The
above may be
modified as
necessary)
10
20.
记分方式 GRADING SYSTEM
A. 十三级等级制 Letter Grading
B. 二级记分制（通过/不通过） Pass/Fail Grading
课程审批 REVIEW AND APPROVAL
21.
本课程设置已经过以下责任人/委员会审议通过
This Course has been approved by the following person or committee of authority
本课程经生物系本科教学指导委员会审议通过。
This Course has been approved by Undergraduate Teaching Steering Committee of Department of Biology.
