nca {clinPK} | R Documentation |
Perform an NCA based on a NONMEM-style dataset
nca(data = NULL, dose = 100, tau = 6, method = "log_linear", scale = list(auc = 1, conc = 1), dv_min = 0.001)
data |
data.frame with time and dv columns |
dose |
dose amount |
tau |
dosing frequency |
method |
'log_linear' or 'linear' |
scale |
list with scaling for auc and concentration ('conc') |
dv_min |
minimum concentrations, lower observations will be set to this value |
data <- data.frame(time = c(0, 2, 4, 6, 8, 12, 16), dv = c(0, 10, 14, 11, 9, 5, 1.5)) nca(data)