Corrected the Coverage of Credible Sets from Bayesian Genetic Fine Mapping


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Documentation for package ‘corrcoverage’ version 1.0.0

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.zj_abf Internal function: Simulate nrep ABFs from joint Z-score vector
.zj_pp Simulate posterior probabilities of causality from joint Z-score vector
approx.bf.p Find approx. Bayes factors (ABFs)
bf_func Calculate ABFs from Z scores
cor2 Correlation matrix of SNPS
corrcov Corrected coverage estimate using Z-scores and mafs
corrcov_bhat Corrected coverage estimate using estimated effect sizes and their standard errors
corrcov_CI Confidence interval for corrected coverage estimate using Z-scores and mafs
corrcov_CI_bhat Confidence interval for corrected coverage estimate using estimated effect sizes and their standard errors
corrcov_nvar Corrected coverage estimate using Z-scores and mafs (fixing nvar)
corrcov_nvar_bhat Corrected coverage estimate using estimated effect sizes and their standard errors (fixing nvar)
corrected_cov Corrected coverage estimate of the causal variant in the credible set
corrected_cs Corrected credible set with desired coverage of the CV
corrected_cs_bhat Corrected credible set with desired coverage of the CV
credset Credible set of genetic variants
credsetC Credible set of variants from matrix of PPs
credsetmat Obtain credible sets from a matrix of posterior probabilities
est_mu Estimate the true effect at the causal variant using Z-scores and MAFs
est_mu_bhat Estimate the true effect at the causal variant using estimated effect sizes and their standard errors
logsum logsum
logsum_matrix logsum rows of a matrix
ppfunc Find PPs of SNPs from Z-scores
ppfunc.mat Find PPs of SNPs from matrix of Z-scores
prop_cov Proportion of credible sets containing the causal variant
pvals_pp Find PPs for SNPs and null model from P-values and MAFs
Var.data.cc Variance of the estimated effect size for case-control data
z0_pp Find PPs for SNPs and null model from Z-scores and MAFs
zj_pp Simulate posterior probabilities of causality from joint Z-score vector
zj_pp_arma Obtain pp from a matrix of Zj and ERR
z_sim Simulate marginal Z-scores from joint Z-score vector